International Review of Ophthalmology ›› 2022, Vol. 46 ›› Issue (5): 443-448.doi: 10.3760/ cma.j.issn.1673-5803.2022.05.011

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Research progress on persistent pupillary membrane

Zhou Linglin1, Wan Xiuhua2   

  1. 1 Department of Ophthalmology, People’s Hospital of Quzhou, Zhejiang 324000, China; 2 Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2021-11-04 Online:2022-10-22 Published:2022-11-04
  • Contact: Wan Xiuhua, Email: xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • Supported by:
    Beijing Hospitals Authority Clinical Medicine Development Special Funding(XMLX202133); National Natural Science Foundation of China(82171037)

Abstract: Existing studies believe that occurrence of persistent pupillary membrane may be caused by macrophage phagocytosis dysfunction and persistent synthetic activity of fibroblasts, but there are also case reports considering which related to maternal infectious factors during pregnancy. Its clinical morphology is quite different, and its impact on vision is also different. At present, its treatment is mainly based on the size of the residual membrane and whether it affects vision. The treatment methods mainly include drugs, lasers and surgery. (Int Rev Ophthalmol, 2022, 46: 443-448)

Key words: persistent pupillary membrane